Steroid 12 alpha Hydroxylase
《英文msh詞典》Steroid 12 alpha Hydroxylase
[入口詞] Steroid 12 alpha Hydroxylase
[主題詞] Steroid 12-alpha-Hydroxylase
[英文釋義] A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP8B1gene,converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol.
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